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http://hdl.handle.net/11718/23194| Title: | Estimation of log‐odds ratio from group testing data using firth correction |
| Authors: | Roy, Surupa Banerjee, Tathagata |
| Keywords: | Eexposure status;Firth correction;Maximum likelihood estimate;Prevalence of a disease;Sensitivity;Specificity |
| Issue Date: | 15-Jan-2019 |
| Publisher: | Wiley |
| Citation: | Roy, S., & Banerjee, T. (2019). Estimation of log-odds ratio from group testing data using Firth correction. Biometrical Journal: Journal of Mathematical Methods in Biosciences, 61(3), 714-728. doi:https://doi. org/10.1002/bimj.201800125 |
| Abstract: | We consider the estimation of the prevalence of a rare disease, and the log‐odds ratio for two specified groups of individuals from group testing data. For a low‐prevalence disease, the maximum likelihood estimate of the log‐odds ratio is severely biased. However, Firth correction to the score function leads to a considerable improvement of the estimator. Also, for a low‐prevalence disease, if the diagnostic test is imperfect, the group testing is found to yield more precise estimate of the log‐odds ratio than the individual testing. |
| URI: | http://hdl.handle.net/11718/23194 |
| ISSN: | 15214036 |
| Appears in Collections: | Journal Articles |
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