Please use this identifier to cite or link to this item: http://hdl.handle.net/11718/25195
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dc.contributor.authorTandon D.
dc.contributor.authorHaque M.M.
dc.contributor.authorSaravanan R.
dc.contributor.authorShaikh S.
dc.contributor.authorSriram P.
dc.contributor.authorDubey A.K.
dc.contributor.authorMande S.S.
dc.date.accessioned2022-02-11T10:13:51Z-
dc.date.available2022-02-11T10:13:51Z-
dc.date.issued2018
dc.identifier.citationTandon, D., Haque, M. M., Saravanan, R., Shaikh, S., Sriram, P., Dubey, A. K., & Mande, S. S. (2018). A snapshot of gut microbiota of an adult urban population from Western region of India. PLoS ONE, 13(4). https://doi.org/10.1371/journal.pone.0195643
dc.identifier.issn19326203
dc.identifier.urihttps://www.doi.org/10.1371/journal.pone.0195643
dc.identifier.urihttp://hdl.handle.net/11718/25195-
dc.description.abstractThe human gut microbiome contributes to a broad range of biochemical and metabolic functions that directly or indirectly affect human physiology. Several recent studies have indicated that factors like age, geographical location, genetic makeup, and individual health status significantly influence the diversity, stability, and resilience of the gut microbiome. Of the mentioned factors, geographical location (and related dietary/socio-economic context) appears to explain a significant portion of microbiome variation observed in various previously conducted base-line studies on human gut microbiome. Given this context, we have undertaken a microbiome study with the objective of cataloguing the taxonomic diversity of gut microbiomes sampled from an urban cohort from Ahmedabad city in Western India. Computational analysis of microbiome sequence data corresponding to 160 stool samples (collected from 80 healthy individuals at two time-points, 60 days apart) has indicated a Prevotella-dominated microbial community. Given that the typical diet of participants included carbohydrate and fibre-rich components (predominantly whole grains and legumebased preparations), results appear to validate the proposed correlation between diet/geography and microbiome composition. Comparative analysis of obtained gut microbiome profiles with previously published microbiome profiles from US, China, Finland, and Japan additionally reveals a distinct taxonomic and (inferred) functional niche for the sampled microbiomes. � 2018 Tandon et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.language.isoen_US
dc.publisherPublic Library of Science
dc.relation.ispartofPLoS ONE
dc.titleA snapshot of gut microbiota of an adult urban population from Western region of India
dc.typeArticle
dc.rights.licenseCC BY
dc.contributor.affiliationBio-Sciences R and D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India
dc.contributor.affiliationTata Chemicals Ltd., Innovation Centre, Ambedveth, Mulshi, Pune, Maharashtra, India
dc.contributor.affiliationVeeda Clinical Research Pvt. Ltd., Near IIM, Ambawadi, Ahmedabad, Gujarat, India
dc.contributor.affiliationGenotypic Technology (P) Ltd., Poojari Layout, Bangalore, India
dc.contributor.institutionauthorTandon, D., Bio-Sciences R and D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India
dc.contributor.institutionauthorHaque, M.M., Bio-Sciences R and D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India
dc.contributor.institutionauthorSaravanan, R., Tata Chemicals Ltd., Innovation Centre, Ambedveth, Mulshi, Pune, Maharashtra, India
dc.contributor.institutionauthorShaikh, S., Veeda Clinical Research Pvt. Ltd., Near IIM, Ambawadi, Ahmedabad, Gujarat, India
dc.contributor.institutionauthorSriram, P., Genotypic Technology (P) Ltd., Poojari Layout, Bangalore, India
dc.contributor.institutionauthorDubey, A.K., Tata Chemicals Ltd., Innovation Centre, Ambedveth, Mulshi, Pune, Maharashtra, India
dc.contributor.institutionauthorMande, S.S., Bio-Sciences R and D Division, TCS Research, Tata Consultancy Services Ltd., Hadapsar Industrial Estate, Pune Maharashtra, India
dc.description.scopusid56747626800
dc.description.scopusid56608672700
dc.description.scopusid57191924908
dc.description.scopusid57209518910
dc.description.scopusid57019971100
dc.description.scopusid57203217778
dc.description.scopusid35313971100
dc.identifier.doi10.1371/journal.pone.0195643
dc.identifier.issue4
dc.identifier.volume13
Appears in Collections:Open Access Journal Articles

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