Please use this identifier to cite or link to this item: http://hdl.handle.net/11718/25417
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dc.contributor.authorModi, K. D.
dc.contributor.authorAhmed, Md Ishaq
dc.contributor.authorChandwani, Rajesh
dc.contributor.authorHari Kumar, K. V. S.
dc.date.accessioned2022-02-11T10:17:21Z
dc.date.available2022-02-11T10:17:21Z
dc.date.issued2015
dc.identifier.citationModi, K. D., Ahmed, M. I., Chandwani, R., & Kumar, K. V. S. H. (2015). Prevalence of vitamin D deficiency across the spectrum of glucose intolerance. Journal of Diabetes and Metabolic Disorders, 14(1). https://doi.org/10.1186/s40200-015-0179-5
dc.identifier.issn22516581
dc.identifier.urihttps://www.doi.org/10.1186/s40200-015-0179-5
dc.identifier.urihttp://hdl.handle.net/11718/25417
dc.description.abstractBackground: Vitamin D deficiency (VDD) is inversely associated with insulin resistance. We studied the prevalence of VDD across the spectrum of glucose intolerance, including normal glucose tolerance (NGT), prediabetes (PD) and type 2 diabetes (T2D). Methods: We conducted this cross-sectional, observational study by serially including the PD and T2D patients seen between June and December 2014. We excluded patients with major illness, secondary diabetes and use of vitamin D or glucocorticoids. VDD was defined as serum 25-hydroxy vitamin D (25OHD) less than 30 ng/mL. The study population was divided into 3 groups: T2D (Group 1; n = 274), PD (Group 2; n = 62) and NGT controls (Group 3; n = 270) for the analysis and appropriate statistical methods were used. Results: The study participants (n = 606, 28 % males) had a mean age of 43.2 ± 13.6 years, BMI of 27.7 ± 5.9 kg/m2 , HbA1c of 6.6 ± 2 % and mean 25OHD of 18.8 ± 15.7 ng/mL. VDD was seen in 85 % of the entire study population including 84 % in T2D, 77 % in prediabetes and in 87 % of the controls. The mean 25OHD levels were lower in the control group (16.8 ng/mL) when compared with T2D and prediabetes (19.9 and 22.4 ng/mL) respectively (P = 0.0124). Univariate analysis showed higher odds of VDD in females (P < 0.0001) but no association with diabetes, age, BMI and HbA1c. Conclusion: Our data showed that VDD is prevalent in the majority of the population, irrespective of the underlying glucose intolerance. Further studies are required to determine the association between the vitamin D and diabetes.
dc.language.isoen_US
dc.publisherBioMed Central Ltd.
dc.relation.ispartofJournal of Diabetes and Metabolic Disorders
dc.subjectIndia
dc.subjectPrediabetes
dc.subjectPrevalence
dc.subjectType 2 diabetes
dc.subjectVitamin D
dc.titlePrevalence of vitamin D deficiency across the spectrum of glucose intolerance
dc.typeArticle
dc.rights.licenseCC BY
dc.contributor.affiliationDepartment of Endocrinology, Dr Modi's Clinic, Mehdipatnam, Hyderabad, India
dc.contributor.affiliationDepartment of Personnel and Industrial Relations, IIM, Ahmedabad, India
dc.contributor.affiliationDepartment of Endocrinology, Command Hospital, Chandimandir, Haryana, India
dc.contributor.institutionauthorModi, K.D., Department of Endocrinology, Dr Modi's Clinic, Mehdipatnam, Hyderabad, India
dc.contributor.institutionauthorAhmed, M.I., Department of Endocrinology, Dr Modi's Clinic, Mehdipatnam, Hyderabad, India
dc.contributor.institutionauthorChandwani, R., Department of Personnel and Industrial Relations, IIM, Ahmedabad, India
dc.contributor.institutionauthorKumar, K.V.S.H., Department of Endocrinology, Command Hospital, Chandimandir, Haryana, India
dc.description.scopusid16241962000
dc.description.scopusid56699217000
dc.description.scopusid55992047100
dc.description.scopusid23489156200
dc.identifier.doi10.1186/s40200-015-0179-5
dc.identifier.issue1
dc.identifier.volume14
Appears in Collections:Open Access Journal Articles

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