Browsing by Author "Ruokolainen J."

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Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations

Jha N.K.; Ojha S.; Jha S.K.; Dureja H.; Singh S.K.; Shukla S.D.; Chellappan D.K.; Gupta G.; Bhardwaj S.; Kumar N.; Jeyaraman M.; Jain R.; Muthu S.; Kar R.; Kumar D.; Goswami V.K.; Ruokolainen J.; Kesari K.K.; Singh S.K.; Dua K. (Humana Press Inc., 2021)

The coronavirus disease 2019 (COVID-19) pandemic is an issue of global significance that has taken the lives of many across the world. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible ...
The FBXW7-NOTCH interactome: A ubiquitin proteasomal system-induced crosstalk modulating oncogenic transformation in human tissues

Kar R.; Jha S.K.; Ojha S.; Sharma A.; Dholpuria S.; Raju V.S.R.; Prasher P.; Chellappan D.K.; Gupta G.; Kumar Singh S.; Paudel K.R.; Hansbro P.M.; Kumar Singh S.; Ruokolainen J.; Kesari K.K.; Dua K.; Jha N.K. (John Wiley and Sons Inc, 2021)

Background: Ubiquitin ligases or E3 ligases are well programmed to regulate molecular interactions that operate at a post-translational level. Skp, Cullin, F-box containing complex (or SCF complex) is a multidomain E3 ...