Browsing by Author "Sharma A."
Now showing items 1-2 of 2
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A "NOTCH" deeper into the epithelial-to-mesenchymal transition (EMT) program in breast cancer
Kar R.; Jha N.K.; Jha S.K.; Sharma A.; Dholpuria S.; Asthana N.; Chaurasiya K.; Singh V.K.; Burgee S.; Nand P. (MDPI AG, 2019)Notch signaling is a primitive signaling pathway having various roles in the normal origin and development of each multicellular organisms. Therefore, any aberration in the pathway will inevitably lead to deadly outcomes ... -
The FBXW7-NOTCH interactome: A ubiquitin proteasomal system-induced crosstalk modulating oncogenic transformation in human tissues
Kar R.; Jha S.K.; Ojha S.; Sharma A.; Dholpuria S.; Raju V.S.R.; Prasher P.; Chellappan D.K.; Gupta G.; Kumar Singh S.; Paudel K.R.; Hansbro P.M.; Kumar Singh S.; Ruokolainen J.; Kesari K.K.; Dua K.; Jha N.K. (John Wiley and Sons Inc, 2021)Background: Ubiquitin ligases or E3 ligases are well programmed to regulate molecular interactions that operate at a post-translational level. Skp, Cullin, F-box containing complex (or SCF complex) is a multidomain E3 ...